Carbon 60 (C60): Health Benefits and How to Use It (2024)

Carbon 60 (C60): Health Benefits and How to Use It

Carbon 60 or C60 is one of the biggest buzzes lately in the health world. It is touted as a miracle molecule for anti-aging, energy, skin health, and more. C60 was an exciting find when it was discovered back in 1985.

In fact, the scientists who found it were awarded the Nobel Prize in Chemistry in 1996 for their discovery. You will want to learn more about this amazing compound and what it can do for your health!

C60 is a type of fullerene made up of 60 carbon atoms. These 60 atoms bonded together offer antioxidant benefits and can fight free radicals effectively. This can decrease oxidative stress, chronic inflammation, signs of aging, various symptoms, and the risk of chronic health issues. I bet I caught your interest. If you want to learn more about the benefits of C60, read on!

In this article, you will learn what C60 is. I will discuss the connection between C60 and mitochondrial health. You will learn about the potential health benefits of C60. I will go over potential side effects and the best dosage for C60. I will explain how to select the best C60 supplement and recommend my favorite brand for C60 supplementation.

What Is C60

Carbon 60 or also known as C60 is the most common fullerene. A fullerene is a type of carbon. It is a large spheroidal molecule made of a hollow cage of atoms. It basically looks like a hollow soccer ball. C60 is bade up of 60 carbon atoms — hence the name.

These 60 atoms bond together. When bonded, they can interact with and fight free radicals in the environment thanks to their antioxidant properties. Antioxidants are substances that can fight oxidation. You probably know that vegetables and fruits are high in antioxidants, and as a result, they can decrease oxidative stress and related inflammation in your body.

As a result, they may help to reduce signs of aging, including visible signs on your skin and the risk of age-related health issues. Oxidative stress may play a role in a variety of health issues, including cancer, heart disease, neurodegenerative diseases (e.g., Parkinson’s disease, Alzheimer’s disease), and diabetes.

Antioxidants may help to reduce the risk and slow the progress of these diseases. Due to its antioxidant properties, C60 supplements may help to reduce signs of aging and chronic health issues.

C60 and Mitochondrial Health

The mitochondria are the powerhouse of your cells. We’ve all heard this a million times since high school biology class. But what does that even mean?

Mitochondria are specialized structures found in every cell of the human body with the exception of red blood cells. Mitochondria contain their own DNA. They basically serve as batteries to power a variety of functions in your body. They are responsible for generating 90% of cellular energy in the form of adenosine triphosphate (ATP) and for assisting metabolic functions.

Mitochondria are located in differing concentrations in various tissues throughout the body. They are designed to serve the purpose of those specific tissues.

For example, the mitochondria in your liver help to convert ammonia into a less toxic waste substance. The mitochondria support cellular respiration and energy production. It plays a critical role in calcium homeostasis, cell growth, and cell death.

Without healthy mitochondria, your cells and, thus, your body cannot function well. Mitochondrial dysfunction may lead to fatigue, muscle aches and pains, cardiovascular issues, nervous system dysfunction, respiratory problems, migraines and headaches, hormonal issues, liver and kidney problems, and many other health issues. This is where C60 comes in, to reduce your risk of mitochondrial issues.

Thanks to its antioxidant properties, C60 may help to fight oxidative stress, toxin exposure, and inflammation which all may compromise mitochondrial function. 2014 research published in the International Journal of Biology and Biomedical Engineering has found that C60 may have potential as a mitochondrial-targeted antioxidant (1).

Health Benefits of C60

C60 may offer many health benefits, including anti-inflammatory benefits, anti-aging effects, improved blood sugar, reducing the risk of diabetes, supporting brain health, supporting cancer recovery, improved energy, supporting a healthy libido, aiding recovery and performance, reducing the effects of EMF and radiation, improving skin health, and supporting vision health. Let’s discuss these benefits.

Anti-Inflammatory

C60 may help to reduce inflammation which may benefit various inflammatory conditions from skin problems to joint issues. A 2016 study published in the Journal of Nanotechnology, has found that C60 may help to reduce skin inflammation related to atopic dermatitis in mice (5).

According to a 2019 study published in the International Journal of Nanomedicine, C60 derivatives have helped to reduce joint inflammation and joint damage in rats by inhibiting macrophage activation (4). According to a 2007 study published in the Journal of Immunology, it may also help to reduce allergic response and related inflammation (5).

Anti-Aging

C60 may also have some anti-aging effects by reducing the signs of aging and improving lifespan. A 2012 study published in Biomaterials has found that C60 may help to improve the lifespan of rats (6).

A 2008 study on mice published in the Neurobiology of Aging has found that C60 may help to extend lifespan and improve cognition (7). A 2008 study published in the Journal of the American Academy of Dermatology has found that fullerene, like C60, may help to reduce wrinkles as a sign of skin aging (8).

Blood Sugar and Diabetes

C60 may help to support your blood sugar levels and reduce the risk of diabetes. According to a 2020 study published in Neurochemical Research, C60 may help to reduce hypoglycemia-related health issues (9).

According to 2020 research published in Food and Chemical Toxicology, C60 supplementation may help to support glucose and lipid homeostasis and support gut health (10).

Brain Health

C60 may also help to improve your brain health and reduce the risk of cognitive issues. According to a 2008 study on mice published in the Neurobiology of Aging, C60 may help to extend lifespan and improve cognition (7).

A 2007 study published in the Journal of Nanoscience and Nanotechnology has found that C60 may help to support cognitive performance (11). According to a 2017 rat study published in the Journal of Alzheimer’s Disease, C60 may help to improve learning and memory pathways (12).

Cancer Support

C60 supplementation may also be a complimentary part of cancer support. A 2021 study on mice published in the Journal of Colloid and Interface Sciences, C60, in photodynamic cancer therapy experiments, “was internalized by cancer cells and induced cell apoptosis without noticeable toxicity”, supporting cancer therapy (13).

2020 research published in Pharmaceutics, C60 may support the treatment of hepatocellular carcinoma in rats and reduce liver alterations related to the condition (14). A 2020 study published in the International Journal of Nanomedicine has found that water-soluble C60 may be protective against lung damage related to bleomycin, an anti-cancer drug (15).

Improved Energy

As you learned already, C60 may help to improve mitochondrial health and energy production. Thus, it’s not surprising that it may help with energy (1, 2). C60 can collect inside mitochondria which may also help the process of energy protection by acting as a buffer against reactive oxygen species (ROS), which can slow energy production.

According to a 2014 study published in Connective Tissue Research, C60 may help to improve muscle endurance (16). It may help to improve stamina and energy.

Supports Healthy Libido

C60 may also help to support a healthy libido by balancing hormones and activating pregnenolone. Pregnenolone is a precursor to all hormones.

According to a 2021 Forbes article interviewing Kenneth Swartz, an expert in the field of C60 supplements, C60 may help to improve testosterone levels in men, estrogen levels in women, and balance hormone levels by stimulating pregnenolone production (17). This may help to improve libido, energy, and mental clarity.

Muscle Recovery and Performance

Whether you are an athlete, a weekend warrior, or completely new to exercise, C60 may help you with muscle recovery and performance. According to a 2014 study published in Connective Tissue Research, C60 may help to improve muscle endurance (16).

A 2017 study on rats published in the Journal of Nanobiotechnology has found that C60 may help to improve and reduce the risk of skeletal muscle fatigue (17). As a result, it may also help to increase muscle endurance.

Radiation and EMF Mitigation

C60 may also act as a buffer against radiation and EMFs. This is great news since with wifi, cell phones, computers, and 5G, we are all exposed to lots of radiation, more than ever before. According to a 2009 study published in Free Radical Biology and Medicine, C60 may offer radioprotective and antioxidant benefits (19).

According to a 2009 study published in Toxicology, it may be protective against UV radiation, too (20). According to a 2010 study published in Toxicology and Applied Pharmacology, C60 may help to reduce mitochondrial dysfunction and immune health issues related to ionizing radiation in mice (21).

Vision Support

As a substance with antioxidant benefits, C60 may be beneficial for your vision. According to 2022 research published in Biomedical Research International, antioxidants may help to reduce eye aging (22).

It may help to reduce oxidative stress, promote retinal health and improve eye muscle flexibility. However, we still need more research evidence on the benefits of C60 on vision.

Skin Health

C60 may also help to improve your skin health and reduce signs of aging of your skin. According to a 2016 study on mice published in the Journal of Nanotechnology, C60 may help to reduce skin inflammation related to atopic dermatitis (5).

According to a 2008 study published in the Journal of the American Academy of Dermatology, C60 may help to decrease wrinkles (8). A 2009 mouse study published in Toxicology has found that C60 may be protective against UV radiation and related skin damage (20).

Potential Side Effects

Based on current research evidence, C60 isn’t toxic and is generally safe for humans. According to a 2016 review published in Experimental Dermatology, skin reactions related to C60 are very uncommon in humans and animals (23).

According to a 2012 study published in the Journal of Toxicological Sciences and another 2012 study published in Biomaterials, C60 is not toxic to rats (24, 25). However, we still need more research evidence to have a full understanding. It’s always important to talk to your doctor first.

Best Dosage

We don’t have a complete understanding of the most effective dosage for C60. We need more research on the benefits and dosage for humans. Based on animal studies, the best range is range from 0.4 to 5 milligrams per kilogram (mg/kg) of body weight, typically when dissolved in olive oil.

When looking at the effects of C60, specifically on the skin, both human and animal studies show a range between less than 0.0005 percent to 0.05 percent.

If you are using C60, I recommend that you follow the directions on your supplement and talk to your doctor for guidance. The general dosage recommendation is 1 teaspoon a day for an average 150-lb person.

As with every supplement, starting at a lower dose is better to see how you are doing on it. If you are not experiencing any reactions, you can increase the dose until you find your sweet spot within the recommendation range.

How to Purchase It

If you are looking to use C60 as a supplement, I recommend that you buy from a trusted brand. There are different ways to take C60. Some supplements use olive oil, while others use MCT coconut oil, avocado oil, or black seed (Nigella sativa) oil).

You may even find them in capsule form with one of these carrier oils. If you are choosing a liquid form, I recommend that you pick a dark bottle and store it in a cool, dark pace. This is important because, according to animal studies, C60 with olive oil, when exposed to light, can be toxic to mice.

While this may not be an issue for humans, olive oil is best to be stored in darker bottles anyways. If you look in your cabinet, you probably find that your olive oil is in dark green, brown, or black bottles.

When looking for a high-quality C60 product, I recommend looking for the following things:

99.9% Pure Sublimated
Dark Amber Bottle
Certified Organic Oils
Solvent-Free
3rd party Tested
Highly Concentrated, Between 99.95% to 99.99% Pure C60

Introducing C60 Purple Power

If you’ve been following me for a while, you know that I only use and recommend high-quality supplements from trusted brands. After searching for the right C60 supplement, I found that C60 Purple Power is the best one out there. This is what I use myself and recommend to my patients, family, and friends.

They offer different products with olive oil, coconut oil, and avocado oil, depending on your preferences. They are using the highest quality C60 made with 100% Certified Organic, healthy, farm-direct carrier oils. These products are third-party tested for purity, concentration, and bioavailability.

They are manufactured in an FDA-compliant facility to meet governmental standards. Their products are purified through sublimation, and most importantly, they are never exposed to solvents. I recommend that you try C60 Purple Power. You won’t regret it. Use the Discount Code JOCKERS for 15% OFF.

Final Thoughts

60 is a type of fullerene made up of 60 carbon atoms. These 60 atoms bonded together offer antioxidant benefits and can fight free radicals effectively. This can decrease oxidative stress, chronic inflammation, signs of aging, various symptoms, and the risk of chronic health issues.

I recommend that you try C60 to improve your health and well-being. Follow my tips in this article for selecting the best brand, or better yet, try my recommendation, C60 Purple Power. Use the Discount Code JOCKERS for 15% OFF.

Sources in This Article Include:

1. Can C60 fullerene demonstrate properties of mitochondria-targeted antioxidant from the computational point of view? V. A. Chistyakov, International Journal of Biology and Biomedical Engineering Link Here

2. Gonchar OO, Maznychenko AV, Klyuchko OM, Mankovska IM, Butowska K, Borowik A, Piosik J, Sokolowska I. C60 Fullerene Reduces 3-Nitropropionic Acid-Induced Oxidative Stress Disorders and Mitochondrial Dysfunction in Rats by Modulation of p53, Bcl-2 and Nrf2 Targeted Proteins. Int J Mol Sci. 2021 May 21;22(11):5444. doi: 10.3390/ijms22115444. PMID: 34064070

3.Shershakova N, Baraboshkina E, Andreev S, Purgina D, Struchkova I, Kamyshnikov O, Nikonova A, Khaitov M. Anti-inflammatory effect of fullerene C60 in a mice model of atopic dermatitis. J Nanobiotechnology. 2016 Jan 25;14:8. doi: 10.1186/s12951-016-0159-z. PMID: 2681023

4. Pei Y, Cui F, Du X, Shang G, Xiao W, Yang X, Cui Q. Antioxidative nanofullerol inhibits macrophage activation and development of osteoarthritis in rats. Int J Nanomedicine. 2019 Jun 6;14:4145-4155. doi: 10.2147/IJN.S202466. PMID: 31239673

5. Fullerene Nanomaterials Inhibit the Allergic Response. Link Here

6. Tarek Baati, Fanchon Bourasset, Najla Gharbi, Leila Njim, Manef Abderrabba, Abdelhamid Kerkeni, Henri Szwarc, Fathi Moussa, The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene, Biomaterials, Volume 33, Issue 19, 2012 Link Here

7. Kevin L. Quick, Sameh S. Ali, Robert Arch, Chengjie Xiong, David Wozniak, Laura L. Dugan,

A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice, Neurobiology of Aging, 2008 Link Here

8. Fullerene is effective against wrinkles JAAD. Link Here

9. Demir, E., Nedzvetsky, V.S., Ağca, C.A. et al. Pristine C60 Fullerene Nanoparticles Ameliorate Hyperglycemia-Induced Disturbances via Modulation of Apoptosis and Autophagy Flux. Neurochem Res 45, 2385–2397 (2020). Link Here

10. Siniša Đurašević, Gorana Nikolić, Ana Todorović, Dunja Drakulić, Snežana Pejić, Vesna Martinović, Dragana Mitić-Ćulafić, Dragana Milić, Tatjana J. Kop, Nebojša Jasnić, Jelena Đorđević, Zoran Todorović,Effects of fullerene C60 supplementation on gut microbiota and glucose and lipid homeostasis in rats, Food and Chemical Toxicology. Link Here

11. Podolski IY, Podlubnaya ZA, Kosenko EA, Mugantseva EA, Makarova EG, Marsagishvili LG, Shpagina MD, Kaminsky YG, Andrievsky GV, Klochkov VK. Effects of hydrated forms of C60 fullerene on amyloid 1-peptide fibrillization in vitro and performance of the cognitive task. J Nanosci Nanotechnol. 2007 Apr-May;7(4-5):1479-85. doi: 10.1166/jnn.2007.330. PMID: 17450915

12. Gordon R, Podolski I, Makarova E, Deev A, Mugantseva E, Khutsyan S, Sengpiel F, Murashev A, Vorobyov V. Intrahippocampal Pathways Involved in Learning/Memory Mechanisms are Affected by Intracerebral Infusions of Amyloid-β25-35 Peptide and Hydrated Fullerene C60 in Rats. J Alzheimers Dis. 2017;58(3):711-724. doi: 10.3233/JAD-161182. PMID: 28482636

13. Lee H, Seok Lee J, Moor KJ, Kim HI, Kim SR, Gim G, Lee J, Kim HH, Fahmy TM, Kim JH, Lee C. Hand-ground fullerene-nanodiamond composite for photosensitized water treatment and photodynamic cancer therapy. J Colloid Interface Sci. 2021 Apr;587:101-109. doi: 10.1016/j.jcis.2020.12.020. Epub 2020 Dec 11. PMID: 33360882

14. Kuznietsova H, Dziubenko N, Herheliuk T, Prylutskyy Y, Tauscher E, Ritter U, Scharff P. Water-Soluble Pristine C60 Fullerene Inhibits Liver Alterations Associated with Hepatocellular Carcinoma in Rat. Pharmaceutics. 2020 Aug 22;12(9):794. doi: 10.3390/pharmaceutics12090794. PMID: 32842595

15. Dong R, Liu M, Huang XX, Liu Z, Jiang DY, Xiao HJ, Geng J, Ren YH, Dai HP. Water-Soluble C60 Protects Against Bleomycin-Induced Pulmonary Fibrosis in Mice. Int J Nanomedicine. 2020 Mar 31;15:2269-2276. doi: 10.2147/IJN.S214056. PMID: 32280219

16. Liu Q, Cui Q, Li XJ, Jin L. The applications of buckminsterfullerene C60 and derivatives in orthopaedic research. Connect Tissue Res. 2014 Apr;55(2):71-9. doi: 10.3109/03008207.2013.877894. Epub 2014 Jan 24. PMID: 24409811

17. This Nobel Prize-Winning Molecule Could Be The Best Thing For Anti-Aging. 2021 Forbes. Link Here

18. Prylutskyy YI, Vereshchaka IV, Maznychenko AV, Bulgakova NV, Gonchar OO, Kyzyma OA, Ritter U, Scharff P, Tomiak T, Nozdrenko DM, Mishchenko IV, Kostyukov AI. C60 fullerene as promising therapeutic agent for correcting and preventing skeletal muscle fatigue. J Nanobiotechnology. 2017 Jan 13;15(1):8. doi: 10.1186/s12951-016-0246-1. PMID: 28086894

19, Andrievsky GV, Bruskov VI, Tykhomyrov AA, Gudkov SV. Peculiarities of the antioxidant and radioprotective effects of hydrated C60 fullerene nanostuctures in vitro and in vivo. Free Radic Biol Med. 2009 Sep 15;47(6):786-93. doi: 10.1016/j.freeradbiomed.2009.06.016. Epub 2009 Jun 17. PMID: 19539750

20. Shinobu Ito, Kazuyoshi Itoga, Masayuki Yamato, Hirohiko Akamatsu, Teruo Okano,The co-application effects of fullerene and ascorbic acid on UV-B irradiated mouse skin,Toxicology 2009. Lnk Here

21. Cai X, Hao J, Zhang X, Yu B, Ren J, Luo C, Li Q, Huang Q, Shi X, Li W, Liu J. The polyhydroxylated fullerene derivative C60(OH)24 protects mice from ionizing-radiation-induced immune and mitochondrial dysfunction. Toxicol Appl Pharmacol. 2010 Feb 15;243(1):27-34. doi: 10.1016/j.taap.2009.11.009. Epub 2009 Nov 13. PMID: 19914272

22. Choo PP, Woi PJ, Bastion MC, Omar R, Mustapha M, Md Din N. Review of Evidence for the Usage of Antioxidants for Eye Aging. Biomed Res Int. 2022 Oct 3;2022:5810373. doi: 10.1155/2022/5810373. PMID: 36225983

23. Fullerene C60 with cytoprotective and cytotoxic potential: prospects as a novel treatment agent in Dermatology? 2012 Link HEre

24. Sub-acute oral toxicity study with fullerene C60 in rats. 2012 Journal of toxicological sciences. Link Here

25. Tarek Baati, Fanchon Bourasset, Najla Gharbi, Leila Njim, Manef Abderrabba, Abdelhamid Kerkeni, Henri Szwarc, Fathi Moussa, The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene, Biomaterials, 2012. Link Here

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Carbon 60 (C60): Health Benefits and How to Use It (2024)